Signs | Symptoms | Treatment
Chondromyxoid fibroma (CMF) is a rare benign bone tumour consisting of fibrous, chondroid and myxoid tissue.
What is the cause for CMF?
- Exact etiology is unknown
Which age group is affected?
- They are common in the age group of 5-30 years
- Girls/women are more affected than males, ratio of 1.7 to 1.
What sites in the body are affected?
- Mostly seen in the metaphysis location in the bone.
- Rarely, diaphysis and epiphysis is involved (more in adults)
- Commonly involved sites are lower limbs (around the knee) followed by pelvis.
- Upper limb involvement is extremely rare.
What are the signs and symptoms of Chondromyxoid fibroma?
- CMF’s are slow growing in nature.
- Pain is common symptom. Of mild and long duration type.
- Bony swelling could be due to the expansion of the underlying bone, which is tender.
- Fractures are rarely encountered.
How is CMF diagnosed?
- Plain radiographs show a pure lytic lesion, eccentrically placed with a well-defined margin and smooth borders Pain is common symptom. Of mild and long duration type.
- Expansion of the bone may be noticed. Appears as if the bone is eaten away at the edge.
- Soap bubble picture may be seen
- MRI may be performed when the clinical and radiological findings allow the surgeon to suspect other causes such as Aneurysmal bone cyst, Non-ossifying fibroma or Fibrous dysplasia. The findings are homogenous in pattern with low intensity.
- An image guided biopsy is performed with a core needle for histopathological evaluation by pathologist.
What is the treatment for Chondromyxoid fibroma?
- Surgical intervention is treatment of choice
- Extended Curettage is performed .https://bonecancer.in/2020/05/15/extended-curettage-2/
- Reconstruction can be performed with either bone grafts or bone cement.
- Recurrence rates are very low for an adequately operated CMF.
- Routine follow up is recommended with plain radiographs to ascertain healing and any recurrence.